Is elective high frequency oscillatory ventilation better than conventional mechanical ventilation in very low birth weight infants?

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Pro/con clinical debate: High-frequency oscillatory ventilation is better than conventional ventilation for premature infants

Arguably one of the most important advances in critical care medicine in recent years has been the understanding that mechanical ventilators can impart harm and that lung-protective ventilation strategies can save lives. High-frequency oscillatory ventilation appears ideally suited for lung protection at first glance. Two camps of opinion exist, however, even in neonates where this modality has...

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Effective Tidal Volume for Normocapnia in Very-Low-Birth-Weight Infants Using High-Frequency Oscillatory Ventilation

PURPOSE Removal of CO₂ is much efficient during high-frequency oscillatory ventilation (HFOV) for preterm infants. However, an optimal carbon dioxide diffusion coefficient (DCO₂) and tidal volume (VT) have not yet been established due to much individual variance. This study aimed to analyze DCO₂ values, VT, and minute volume in very-low-birth-weight (VLBW) infants using HFOV and correlates with...

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Elective High-Frequency Oscillatory Ventilation versus Conventional Ventilation for Acute Pulmonary Dysfunction in Preterm Infants

CV and usually in the first 12 h of life. Data Collection and Analysis: The methodological quality of each trial was independently reviewed by the various authors. The standard effect measures are relative risk (RR) and risk difference (RD). From 1/RD the number needed to treat to produce one outcome were calculated. For all measures of effect, 95% confidence intervals were used. In subgroup an...

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Elective High-Frequency Oscillatory Ventilation Versus Conventional Ventilation for Acute Pulmonary Dysfunction in Preterm Infants

BACKGROUND Respiratory failure due to lung immaturity is a major cause of mortality in preterm infants. Although the use of intermittent positive pressure ventilation (IPPV) in neonates with respiratory failure saves lives, its use is associated with lung injury and chronic lung disease. A newer form of ventilation called high frequency oscillatory ventilation has been shown in experimental stu...

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High frequency oscillatory ventilation was not more effective than conventional ventilation in preterm infants.

Intervention After stratification for gestational age and centre, infants were allocated to HFOV (n=400) or CV (n=397) within 1 hour of birth. HFOV was given by 1 of 3 high frequency oscillator models. Ventilation began at a mean airway pressure of 6–8 cm of water and a frequency of 10 Hz; the amplitude was increased until the infant’s chest was seen to be “bouncing”. CV was given by a time cyc...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2003

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.88.9.833